Author of the award-winning novel Annotations (1995). A graduate of Harvard College, he is a New York Times Fellow at New York University. Keene's work has appeared in Brother to Brother and Shade.

He has received many honors for his work, including four Pushcart Prize nominations, a range of fellowships, AGNI literary journal's 2000 John Cheever Short Fiction Prize and the 2001 Solo Press/Solo Magazine Poetry Prize. He has completed a book of poems, is working on several long fictional works, and currently teaches at Brown University.